CAMPTOTHECIN AND KHAT (CATHA EDULIS FORSK.) INDUCED DISTINCT CELL DEATH PHENOTYPES INVOLVING MODULATION OF C-FLIPL, MCL-1, PROCASPASE-8 AND MITOCHONDRIAL FUNCTION IN ACUTE MYELOID LEUKEMIA CELL LINES

Abstract Background An organic extract of the recreational herb khat (Catha edulis Forsk.) triggers cell death in various leukemia cell lines in vitro.The chemotherapeutics camptothecin, a plant alkaloid topoisomerase I inhibitor, was tested side-by-side with khat in a panel of acute myeloid leukemia cell lines to elucidate mechanisms of toxicity.R

The study explored the technologies that can be used to support Inquiry-Based Learning (IBL) in Natural Science (NS) in Ekurhuleni schools, Gauteng.An interpretivist research philosophy, qualitative research approach and a case study design were employed.Data were collected from participants Course a pied - Femme - Vetements - Chandail - Long sleev

Mashael NUTRI REPAIR CREAM Al-Saeedi, Sahal Al-Hajoj Department of Infection and Immunity, Mycobacteriology Research Section, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia Abstract: Despite the efficacy of antibiotics to protect humankind against many deadly pathogens, such as Mycobacterium tuberculosis, nothing can

Mendelian randomization (MR) uses genetic Apron information to strengthen causal inference concerning the effect of exposures on outcomes.This method has a broad range of applications, including investigating risk factors and appraising potential targets for intervention.MR-Base has become established as a freely accessible, online platform, which

Abstract Background The subjective haptic vertical (SHV) task requires subjects to adjust the roll orientation of Pre-Rolled Cones an object, mostly in the roll plane, in such a way that it is parallel to perceived direction of gravity.Previously we found a tendency for clockwise rod rotations to deviate counter-clockwise and vice versa, indicating